This is very user specific, and depends on a lot of factor. But one can definitely lower the dosage and frequency of medication with regular diet and exercise (after getting the tests and doctor's approval)

A lot of symptoms of thyroid can be managed with Yoga. For example the practice of Yoga aids weight loss, energises the body, improves strength in joints, improves hormonal balance and the functioning of various organs which impact and improve the overall health.

Can you cure hypothyroidism with diet and exercise?

Hypothyroidism

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